In the PressFebruary 6, 2020 Cancer-Causing Culprits Could be Caught by their DNA FingerprintsCauses of cancer are being catalogued through an international study revealing the genetic fingerprints of DNA-damaging processes that drive cancer development, featuring Ludmil Alexandrov, PhD. ➤February 3, 2020 Measuring 'stickiness' of cancer cells could improve prognostic evaluation of tumorsA team of researchers led by the University of California San Diego has created a device that measures how "sticky" cancer cells are, which could improve prognostic evaluation of patient tumors, featuring Anne Wallace, MD. ➤February 3, 2020 With Equal Access to Care, Blacks, Whites Have Similar Prostate Cancer OutcomesSurvival rates are similar for black and white prostate cancer patients who are treated in an equal-access health system, researchers say, featuring Brent Rose, MD. ➤January 31, 2020 Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualizationIn this Oncotarget study, the authors test a novel anti-CEACAM antibody conjugated to a fluorescent dye for detection of multiple CEACAM antigens to enhance visualization of colorectal PDOX tumors and metastases in murine models, featuring Michael Bouvet, MD. ➤January 30, 2020 Increased vegetable consumption fails to reduce risk for prostate cancer progressionThere was evidence that men who ate a diet low in fat and high in fruits and vegetables had a lower risk [for] developing prostate cancer, but that was observational, but with no experimental evidence. This study was developed and conducted by J. Kellogg Parsons, MD, MHS and John Pierce, PhD. ➤January 28, 2020 Stem Cells, CRISPR and Gene Sequencing Technology are Basis of New Brain Cancer ModelResearchers have developed stem cell models that are CRISPR-engineered to have tumor-associated driver mutations in glioblastoma, which harbor essentially all features of patient-derived tumors, including extrachromosomal DNA amplification, featuring senior authors Frank Furnari, PhD and Gene Yeo, PhD. ➤January 28, 2020 New clinical trials treat patients with high risk for cervical cancerDr. Jyoti Mayadev is interviewed regarding new treatments, clinical trials and therapy for patients with cervical cancer and those who have high risk developing it. ➤January 24, 2020 Scientists Trying to 'Hack' Zika Virus to Kill Brain CancerDr. Jeremy Rich is studying how to take advantage of the mechanisms the Zika virus uses to destroy cells in order to improve glioblastoma therapies. ➤January 24, 2020 Zika Virus’ Key into Brain Cells ID’d, Leveraged to Block Infection and Kill Cancer CellsWorking independently, two different UC San Diego research teams identified the same molecule — αvβ5 integrin — using brain organoids, tumor organoids and mouse models, featuring Tariq Rana, PhD, and Jeremy Rich, MD. ➤January 22, 2020 UC San Diego Health Sciences study finds how marijuana accelerates HPV-related head and neck cancerJoseph Califano III, MD, and team used animal and human cell lines to show that THC turns p38 MAPK on and were able to stop the growth of HPV-positive head and neck cancer by turning off the pathway. ➤January 17, 2020 Patient Partners: Good friends and great adventuresDr. Jason Sicklick is a powerful example of what is possible when professionals and families form meaningful partnerships and friendships, in particular for those with rare GISTs. ➤January 16, 2020 Rise in Colorectal Cancer Among People Younger than 50 Continues: Researchers are looking for risk factorsA team of researchers led by Samir Gupta, MD, performed one of the first large-scale studies looking at risk factors for early-onset colorectal cancer. ➤December 27, 2019 Dual target CAR T/natural killer cell therapy shows promise for B-cell malignanciesFate Therapeutics' novel CAR-NK cell construct was designed by the company’s academic collaborator, Dan Kaufman, MD, PhD professor of medicine in the division of regenerative medicine and director of cell therapy at UC San Diego School of Medicine. ➤December 15, 2019 The Fight Against Lymphoma: New Treatments Unveiled at Cancer ConferenceDan Kaufman, MD, PhD, told Healthline that one trial from the MD Anderson Cancer Center in Ohio has engineered cord blood–derived natural killer cells “with an anti-CD19 CAR with early results showing promising efficacy against B-cell lymphomas. ➤December 7, 2019 Ibrutinib + Cirmtuzumab in Patients With CLL/SLL or Mantle Cell LymphomaA phase I/II trial (NCT03088878) that is evaluating the combination of the Bruton's tyrosine kinase inhibitor ibrutinib plus cirmtuzumab in patients with CLL/SLL or MCL, with lead clinician Michael Choi, MD. ➤December 4, 2019 Aptose Appoints Rafael Bejar, MD, PhD, as Chief Medical OfficerAptose Biosciences Inc., a clinical-stage company developing highly differentiated therapeutics targeting the underlying mechanisms of cancer, announced the appointment of Rafael Bejar, MD, PhD, to the position of Senior Vice President, Chief Medical Officer, effective January 1, 2020. ➤December 3, 2019 Immunotherapy is safe following chemoradiotherapy for women with node-positive cervical cancerResults from the NRG Oncology phase I clinical trial NRG-GOG 9929 show that using the immunotherapy drug ipilimumab after chemoradiotherapy (CRT) is tolerated in the curative treatment of women with lymph node-positive cervical cancer, featuring Dr. Jyoti Mayadev. ➤December 2, 2019 UC San Diego doctors offer update on cancer prevention, genetic testing at La Jolla lecture seriesInherited germline factors found to play bigger role than previously recognized featuring Moores Cancer Center Director Scott Lippman, MD. ➤November 21, 2019 Non-Coding DNA Located Outside Chromosomes May Help Drive GlioblastomaExtra DNA scooped up and copied alongside cancer-causing genes helps keep tumors going — elements that could represent new drug targets for brain tumors and other cancers notoriously difficult to treat, featuring co-senior author Jeremy Rich, MD. ➤November 21, 2019 Could this ring-shaped DNA change how we treat cancer?Scientists from UC San Diego and Stanford University show that the circular ecDNA in cancer cells outside the chromosome dramatically increases oncogenes, making tumors more aggressive, with co-senior author Paul Mischel, PhD. ➤
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2023 SymposiumThe 19th Industry/Academia "Next Generation Precision Oncology" Symposium will be held on Thursday, April 27, 2023. Visit our new Symposium site for updates here. 2022 SymposiumThe 18th Industry/Academia "Next Generation Precision Oncology" Symposium was held on Thursday, September 15, 2022. Thank you all for a successful event! See more on our 2022 Symposium page. Featured Symposium HighlightsFeatured past Symposium presentations are below and located here.
2018 Keynote Presentation: Duane Roth Award Lecture
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