
2019 Symposium
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2016 Symposium Featured TalksPlease enjoy the featured talks below from our recent symposium. Thank you! Please note: These videos are for private viewing only. Any unintended use of the videos without consent is prohibited. Moores Cancer Center WelcomeEzra Cohen, MD UC San Diego Moores Cancer Center Duane Roth AwardPresented by Council President Sherri Lightner, City of San Diego Awarded to Dennis Slamon, MD, PhD, UCLA Jonsson Comprehensive Cancer Center Lung cancer KRAS addiction is reversed by disrupting an integrin/lectin membrane complexDavid Cheresh, PhD UC San Diego Moores Cancer Center Keynote Presentation: Molecular diversity of human breast cancer: biologic and therapeutic implicationsDennis Slamon, MD, PhD UCLA Jonsson Comprehensive Cancer Center Immuno-Oncology: Rational combination therapyChris Boshoff, MD, PhD Pfizer Detection and targeting of malignant niche mediated cancer stem cell generationCatriona Jamieson, MD, PhD UC San Diego Moores Cancer Center The role of the microenvironment in modulating tumor angiogenesisNapeoleone Ferrara, MD UC San Diego Moores Cancer Center Revisiting matrix metalloproteinases: allosteric inhibition of MMP9 using a monoclonal antibodyVictoria Smith, PhD Gilead Sciences The bone niche and therapy resistance in bone metastatic prostate cancerChristina Jamieson, PhD UC San Diego Moores Cancer Center Targeting the PI3K-mTOR signaling circuitry in cancer: a bridge from bench to clinicJ. Silvio Gutkind, PhD UC San Diego Moores Cancer Center Anti-ErbB3 therapies – what do we know to dateBirgit Schoeberl, PhD Merrimack Pharmaceuticals Immunotherapy Program at UC San Diego Moores Cancer CenterEzra Cohen, MD UC San Diego Moores Cancer Center Compound development of LADD therapeutics in lung cancerRobert Charnas, PhD Janssen R&D Towards personalized immunotherapy of HNSCCStephen Schoenberger, PhD La Jolla Institute for Allergy and Immunology, Human Longevity Inc. A platform to discover immunotherapeutics for cancerJudith Varner, PhD UC San Diego Moores Cancer Center Biomarker analysis and clinical response in patients with B-cell malignancies treated with anti-CD19 CAR T-cell therapyTony Polverino, PhD Kite Pharma Partnering with patients to accelerate the pace of biomedical researchCorrie Painter, PhD Broad Institute of MIT and Harvard The role of MET exon14 deletion mutations as driver oncogenes in patients with NSCLC and therapeutic intervention with the prototype MET inhibitor glesatinibJames Christensen, PhD Mirati Therapeutics Comprehensive genomic profiling of sarcomas in 175 adolescents and young adults reveals a distinct spectrum of targetable genomic alterationsDeborah Morosini, MD Foundation Medicine Monitoring daily dynamics of early tumor response to targeted therapy in lung cancerHatim Husain, MD UC San Diego Moores Cancer Center Mark Erlander, PhD Trovagene Closing RemarksCatriona Jamieson, MD, PhD UC San Diego Moores Cancer Center Anti-cancer therapies derived from human pluripotent stem cellsDan Kaufman, PhD UC San Diego Moores Cancer Center Symposium Organizer WelcomeIda Deichaite, PhD UC San Diego Moores Cancer Center KEYNOTE SPEAKERSPolyvalent vaccines targeting oncogenic driver pathwaysNora Disis, MD Fred Hutchinson Cancer Research Center Associate Dean for Translational Science University of Washington School of Medicine Molecular diversity of human breast cancer: biologic and therapeutic implications Dennis Slamon, MD, PhD UCLA Jonsson Comprehensive Cancer Center FEATURED SPEAKERSTranslational studies of KTN3379, a novel anti-ErbB3 antibodyDiego Alvarado, PhD Kolltan Pharmaceuticals Immuno-Oncology: Rational combination therapy Chris Boshoff, MD, PhD Pfizer, Inc. Compound development of LADD therapeutics in prostate and lung cancer Robert Charnas, PhD Janssen R&D Lung cancer KRAS addiction is reversed by disrupting an integrin/lectin membrane complex David Cheresh, PhD The role of MET exon14 deletion mutations as driver oncogenes in patients with NSCLC and therapeutic intervention with the prototype MET inhibitor glesatinib Jamie Christensen, PhD Mirati Therapeutics Overview Ezra Cohen, MD Monitoring daily dynamics of early tumor response to targeted therapy in lung cancer Hatim Husain, MD Mark Erlander, PhD Trovagene The role of the microenvironment in modulating tumor angiogenesis Napoleone Ferrara, MD Targeting the PI3K-mTOR signaling circuitry in cancer: a bridge from bench to clinic J. Silvio Gutkind, PhD Detection and targeting of malignant niche mediated cancer stem cell generation Catriona Jamieson, MD, PhD The bone niche and therapy resistance in bone metastatic prostate cancer Christina Jamieson, PhD Anti-cancer therapies derived from human pluripotent stem cells Dan Kaufman, MD, PhD In the wake of homologous repair deficiency: Identifying PARP inhibitor responsive patients Keith Mikule, PhD TESARO Comprehensive genomic profiling of sarcomas in 175 adolescents and young adults reveals a distinct spectrum of targetable genomic alterations Deborah Morosini, MD Foundation Medicine Partnering with patients to accelerate the pace of biomedical research Corrie Painter, PhD Broad Institute of MIT and Harvard Biomarker analysis and clinical response in patients with B-cell malignancies treated with anti-CD19 CAR T-cell therapy Tony Polverino, PhD Kite Pharma Anti-ErbB3 therapies – what do we know to date Birgit Schoeberl, PhD Merrimack Towards personalized immunotherapy of HNSCC Stephen Schoenberger, PhD Head of Cancer Vaccines, Human Longevity Inc. Revisiting matrix metalloproteinases: allosteric inhibition of MMP9 using a monoclonal antibody Victoria Smith, PhD Gilead Sciences A platform to discover immunotherapeutics for cancer Judith Varner, PhD “When you go to an international cancer symposium with 30,000 people, it’s hard to get to the real champion of a project and get their individualized attention. The Moores Cancer Center Translational Oncology Symposium is much more intimate. Industry and academia are on equal footing and there are plenty of opportunities for informal discussions when a lot of synergies develop and collaborations begin or grow.”- Catriona Jamieson, Ph.D., M.D.,
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Symposium Organizers:Scott Lippman, MD Symposium Chair:David Cheresh, PhD |
Ida Deichaite, PhD Symposium Co-Chair:Catriona Jamieson, MD, PhD |



























